Experimental Yersinia-triggered reactive arthritis: effect of a 3-week course of ciprofloxacin
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چکیده
منابع مشابه
Ciprofloxacin v placebo for treatment of Yersinia enterocolitica triggered reactive arthritis.
Patients with yersinia triggered reactive arthritis were double blind randomly allocated to receive treatment with ciprofloxacin 500 mg twice daily orally or placebo during three months. The diagnosis was made by serology (specific IgA and IgG antibodies to yersinia outer membrane proteins (yops)), positive culture, and/or demonstration of Yersinia enterocolitica antigen in colon biopsy specime...
متن کاملIgA-anti-yersinia antibodies in yersinia triggered reactive arthritis.
Patients who develop reactive arthritis after yersinia enteritis are characterised by high and persisting IgA-anti-yersinia antibodies. We have further analysed the humoral immune response to yersinia in this condition. Total concentrations of IgM, IgG, IgA, and secretory IgA in the serum and specific anti-yersinia antibodies belonging to IgA1, IgA2, or secretory IgA were compared in patients w...
متن کاملEffect of a three month course of ciprofloxacin on the outcome of reactive arthritis.
BACKGROUND Treatment of reactive arthritis (ReA) with antibiotics has so far remained controversial. Eradication of the causative microbe appears logical, but short term antibiotic treatment has no beneficial effect on the outcome of ReA. OBJECTIVE To evaluate the effect of a three month course of ciprofloxacin on ReA. METHODS In a randomised, double blind, placebo controlled trial, between...
متن کاملIntestinal permeability in patients with yersinia triggered reactive arthritis.
The passive intestinal permeability of patients with yersinia triggered reactive arthritis was studied using different sized polyethylene glycols (PEGs) contained in a mixture of PEG 400 and PEG 1000. The investigation was carried out at least one year after the onset of yersinia infection, and patients had neither acute gastrointestinal nor joint symptoms. The control groups included patients ...
متن کاملYersinia specific immune complexes in the synovial fluid of patients with yersinia triggered reactive arthritis.
Yersinia specific immune complexes were demonstrated in the synovial fluid of three patients out of 12 with yersinia triggered reactive arthritis. They were not detectable in the synovial fluid of any of the 16 control patients, including nine with reactive arthritis triggered by factors other than yersiniae. Platelet reactive IgG was detectable in the synovial fluid of eight out of the 12 pati...
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ژورنال
عنوان ژورنال: Rheumatology
سال: 1997
ISSN: 1462-0324,1462-0332
DOI: 10.1093/rheumatology/36.5.541